Have you been feeling stuck, self-critical, or weighed down by depression or anxiety? You’re not alone—and promising new research shows that psilocybin, the active compound in “magic mushrooms,” may offer a path toward lasting relief.
What the 2023 Clinical Trial Found
In 2023, a major phase 2b clinical trial by JAMA explored psilocybin’s potential for people living with treatment-resistant depression—the kind of depression that doesn’t get better with standard medications.
Participants were given a single dose of synthetic psilocybin (either 25mg, 10mg, or a very low placebo-like dose of 1mg) in a supportive, therapeutic setting. The results were striking:
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37% of participants in the 25mg group were in remission at 3 weeks.
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Many reported improvements in mood, outlook, and daily functioning after just one session.
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The benefits weren’t just “feel-good” effects—they reflected measurable clinical improvements.
The study also highlighted the importance of set and setting—participants weren’t just handed psilocybin. They were guided by trained facilitators who helped them prepare beforehand and integrate the experience afterward.
Why This Matters
Most antidepressants require daily use and can come with difficult side effects. Psilocybin, by contrast, works differently—it seems to “reset” rigid thought patterns, helping people reconnect with themselves, process old wounds, and see new possibilities for living.
While not a magic cure, this study adds to a growing body of research showing psilocybin can offer real hope for those who feel they’ve run out of options.
My Work with Psilocybin
As a state-licensed psilocybin facilitator in Oregon and Colorado, I guide individuals through safe, legal, trauma-informed psilocybin sessions. My practice is woman- and queer-owned, rooted in compassion, curiosity, and deep respect for this medicine.
I specialize in supporting people navigating:
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Depression, anxiety, and low self-esteem
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Grief, loss, and life transitions
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Burnout and creative or entrepreneurial challenges
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LGBTQ+ identity and women’s issues
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Shifting critical inner dialogue
Each session includes preparation and integration support, so you’re not left to make sense of the experience alone.
Ready to Take the Next Step?
If you’re curious about whether psilocybin might support your journey, I invite you to book a free exploratory call. Together, we’ll explore your goals, your concerns, and whether this path feels right for you.